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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PRKX All Species: 10.3
Human Site: S33 Identified Species: 16.19
UniProt: P51817 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P51817 NP_005035.1 358 40896 S33 G A P A L C P S P E A L S P E
Chimpanzee Pan troglodytes XP_001145269 358 40936 S33 W A P A L C P S P E A R S P E
Rhesus Macaque Macaca mulatta XP_001086667 358 40973 S33 G A P A L C P S P E A R S P E
Dog Lupus familis XP_852513 341 38934 T27 T P K L V P F T L F T S C A V
Cat Felis silvestris
Mouse Mus musculus Q922R0 355 40448 P30 V S A P A A D P K P R T S S Q
Rat Rattus norvegicus P68182 351 40689 L28 A K A K E D F L R K W E N P P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514495 450 51108 S125 L G S S P P K S S G G S G D C
Chicken Gallus gallus XP_416852 365 41407 P40 T A P S P A G P G S P S A P E
Frog Xenopus laevis Q7ZX15 486 56292 M141 D V S S A E Q M D V A M S K G
Zebra Danio Brachydanio rerio XP_690430 357 40786 A32 A G S P T L P A G A A S L T T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P16912 583 65389 S258 D D E S E E S S S V Q T A K G
Honey Bee Apis mellifera XP_393711 374 42855 H51 V E Q T N F S H L H S W E S A
Nematode Worm Caenorhab. elegans P21137 404 46327 K65 D K A R E D F K Q R W E N P A
Sea Urchin Strong. purpuratus XP_001199876 248 28648
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P06244 397 46057 F71 N E E Q Y K Q F I A Q A R V T
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 93 98 80.1 N.A. 77.3 49.1 N.A. 66 81.3 31.6 73.7 N.A. 38.4 56.6 42 47.7
Protein Similarity: 100 95.5 98.3 85.4 N.A. 84.9 68.4 N.A. 72 87.9 46.2 84.3 N.A. 49.9 72.1 61.1 58.6
P-Site Identity: 100 86.6 93.3 0 N.A. 6.6 6.6 N.A. 6.6 26.6 13.3 13.3 N.A. 6.6 0 6.6 0
P-Site Similarity: 100 86.6 93.3 13.3 N.A. 20 20 N.A. 13.3 40 26.6 20 N.A. 20 6.6 13.3 0
Percent
Protein Identity: N.A. N.A. N.A. N.A. 43 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 62.9 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 0 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 0 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 14 27 20 20 14 14 0 7 0 14 34 7 14 7 14 % A
% Cys: 0 0 0 0 0 20 0 0 0 0 0 0 7 0 7 % C
% Asp: 20 7 0 0 0 14 7 0 7 0 0 0 0 7 0 % D
% Glu: 0 14 14 0 20 14 0 0 0 20 0 14 7 0 27 % E
% Phe: 0 0 0 0 0 7 20 7 0 7 0 0 0 0 0 % F
% Gly: 14 14 0 0 0 0 7 0 14 7 7 0 7 0 14 % G
% His: 0 0 0 0 0 0 0 7 0 7 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 7 0 0 0 0 0 0 % I
% Lys: 0 14 7 7 0 7 7 7 7 7 0 0 0 14 0 % K
% Leu: 7 0 0 7 20 7 0 7 14 0 0 7 7 0 0 % L
% Met: 0 0 0 0 0 0 0 7 0 0 0 7 0 0 0 % M
% Asn: 7 0 0 0 7 0 0 0 0 0 0 0 14 0 0 % N
% Pro: 0 7 27 14 14 14 27 14 20 7 7 0 0 40 7 % P
% Gln: 0 0 7 7 0 0 14 0 7 0 14 0 0 0 7 % Q
% Arg: 0 0 0 7 0 0 0 0 7 7 7 14 7 0 0 % R
% Ser: 0 7 20 27 0 0 14 34 14 7 7 27 34 14 0 % S
% Thr: 14 0 0 7 7 0 0 7 0 0 7 14 0 7 14 % T
% Val: 14 7 0 0 7 0 0 0 0 14 0 0 0 7 7 % V
% Trp: 7 0 0 0 0 0 0 0 0 0 14 7 0 0 0 % W
% Tyr: 0 0 0 0 7 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _